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This particular Assignment references the syllabus chosen for the subject of Life Science, for the January 2024 - December 2024 session. The code for the assignment is LSE-03 and it is often used by students who are enrolled in the B.Sc. Degree.
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1. Describe with appropriate examples the role of environment in the determination of sex.
2. Detail the Watson and Crick model of DNA structure. How did it fit in the data provided by Chargaff?
3. Does the operon concept apply to eukaryotes? Describe a suggested mechanism for gene regulation in eukaryotes.
4. In a randomly mating laboratory population of Drosophila, 4 per cent of the flies have black bodies (black is autosomal recessive, b) and 96 per cent have brown bodies (normal colour, B). If this population is assumed to be in Hardy-Weinberg equilibrium, what are the allelic frequencies of B and b, and the genotypic frequencies of BB and Bb?
5. Detail the molecular basis of mutations.
6. Enlist the different types of lymphocytes. Mention their function, site of differentiation, and the type of immunity imparted by them.
7. Describe any two modern methods for the improvement of crop plants.
8. In peas, Tall (T) is dominant over dwarf (t), Yellow is dominant over green (y), and Smooth (S) is dominant over wrinkled (s). What fraction of the offspring in the following cross would be homozygous recessive for all gene pairs in the cross: YyTtss X YyttSs?
9. (a) How linkage maps are constructed? What is their use in genetic studies?
(b) How many linkage groups would be revealed by an analysis of human genome? Choose the correct answer amongst the choices given below:
i) 2
ii) 13
iii) 23
iv) 46
(c) Determine the order of genes along a chromosome based on the following recombination frequencies:
A - B 8 map units
A - C 28 map units
A - D 25 map units
B - C 20 map units
B - D 33 map units
10. Differentiate between the following pairs:
i) Somatic and gametic mutations
ii) Structural and regulatory genes
iii) Euchromatin and heterochromatin
iv) Cell-mediated and humoral immunity
v) Lytic and Iysogenic cycles
1. Write short notes on the following:
(i) Segregation Law of Mendel
(ii) Hardy Weinberg's law
(iii) X -linked traits in humans
(iv) Epistasis
2. (a) What are multiple alleles? Explain giving a suitable example.
(b) Describe packaging of DNA into chromosome.
3. Differentiate between the following:
(i) Phenotype and genotype
(ii) DNA and RNA
(iii) Deamination and Depurination
(iv) T and B lymphocytes
4. What are autosomal and sex chromosome aneuploidies? Describe few of those found in humans.
5. a) Describe Hershey and Chase experiment that proved that DNA is the hereditary material.
b) Explain lytic cycle of a bacteriophage.
6. (a) Explain Chargaff’s rule.
(b) Define mutagenesis. What are major agents leading to mutagenesis?
7. Explain the model for regulation of the lac operon with the help of a well labelled diagram.
8. Describe in brief the following:
(i) Chemical mutagens
(ii) ABO Blood group system
(iii) Autoimmune diseases
(iv) Genetic counselling
9. (a) Describe Griffith’s experiment to show transformation in DNA.
(b) Genetic engineering can be used for improving nutritional value of food. Explain in detail.
10. Describe the various applications of genetic engineering.
1. लिंग निर्धारण में पर्यावरण की भूमिका को उदाहरण देते हुए विस्तार से समझाइए ।
2. वाटसन और क्रिक के DNA संरचना के मॉडल का वर्णन कीजिए। इसमें चारगॉफ द्वारा दिए गए आँकड़े किस प्रकार सही बैठते हैं?
3. क्या ससीमकेन्द्रकों पर ओपेरॉन संकल्पना लागू होती है? ससीमकेन्द्रक में जीन नियमन की एक क्रियाविधि को विस्तार से बताइए।
4. ड्रोसोफिला मक्खियों की एक यादृच्छिकतः संगम करने वाली प्रयोगशाला समष्टि में 4 प्रतिशत मक्खियों का रंग काला (autosomal recessive यानी अलिंगसूत्री अप्रभावी. black, b) है तथा 96 प्रतिशत का रंग भूरा (normal colour brown B) है। यदि इस समष्टि को हार्डी वाइनबर्ग साम्यावस्था में माना जाए तो B तथा b की युग्मविकल्पी आवृतियाँ और BB तथा Bb की जीनप्ररूपी आवृतियाँ क्या होंगी?
5. उत्परिवर्तनों के आण्विक आधार को विस्तार से समझाइए ।
6. विभिन्न लिम्फोसाइटों की सूची बनाइए। उनके प्रकार्य, विभेदन के स्थल तथा उनसे पैदा होने वाले प्रतिरक्षा प्रकारों का उल्लेख कीजिए ।
7. कृषि पौधों को उन्नत बनाने के किन्हीं दो तरीकों का वर्णन कीजिए।
8.मटरों में बौने (t) से लम्बा (T) प्रभावी है, हरे (y) से पीला (Y) प्रभावी है, और वलीय (s) से गोल (S) प्रभावी है। YyTtss xYyttss संकरण में सभी जीन युग्मों के लिए संततियों का कितना अंश समयुग्मजी अप्रभावी होगा?
9. क) सहलग्नता मानचित्र कैसे बनाए जाते हैं? इनका आनुवंशिक अध्ययनों में क्या उपयोग है?
ख) मानव जीनोम के विश्लेषण से कितने सहलग्न समूहों का पता चलता है? निम्नलिखित मदों में से सही उत्तर चुनिए ।
i) 2
ii) 13
iii) 23
iv) 36
ग) निम्नलिखित पुनर्योगज बारंबारताओं के आधार पर गुणसूत्र में जीनों का क्रम निर्धारित कीजिए:
A-B 8 map units
A-C 28 map units
A-D 25 map units
B-C 20 map units
B-D 33 map units
10. निम्नलिखित युग्मों में अंतर बताइए
i) कायिक और युग्मकी उत्परिवर्तन
ii) संरचनात्मक और नियामक जीन
iii) यूक्रोमैटिन और हेटेरोक्रोमैटिन
iv) कोशिका - माध्यित प्रतिरक्षा और तरल प्रतिरक्षा
v) लयन और लयजनक चक्र
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