1. A) Define the term Biochemistry and briefly explain the origin of Biochemistry.
B) Describe the importance of biochemistry as an interdisciplinary subject.
2. A) Define the following terms with suitable examples: Buffer and pH
B) Explain, why water is considered as universal solvent?
3. A) Describe zwitter ion concept. Calculate the pI of alanine where pK1 and pK2 are 2.34 and 9.69.
B) Write a note on classification of amino acids based on their R-groups.
4. A) What is peptide bond?
B) Distinguish between α-helix and β-sheet structures of proteins?
C) Draw the liner structures of D-glucose and D-ribose.
5. Write a detailed note on biologically important sugar derivatives with suitable examples and draw their structures.
6. A) Write systemic names of isomaltose, maltose and raffinose. Draw their structures.
B) Give a detailed account on glycosaminoglycans.
7. A) What are blood group antigens? Explain them with suitable examples.
B) Write a note on storage lipids?
8. A) Write the structure, shorthand form and occurrence of the given fatty acids?
i) Myristic acid ii) Palmitoleic acid iii) Linoleic acid iv) Arachidonic acid
9. A) Describe the composition and role of biological membranes.
B) Briefly explain classification of eicosanoids and their importance.
10. A) Describe and draw the structure and biological functions of Vitamins A, C, B12 and B1.
B) Define denaturation of DNA and explain the effect of temperature and pH on DNA
1. A) Write a brief note on Friedrcih Wholer’s contribution to the origin of Biochemistry.
B) Discuss important inorganic elements and their biological functions.
2. Define the following bonds/interactions with suitable examples: hydrogen bond, hydrophobic bond, Vander Waals and Electrostatic interactions
3. A) Describe and draw the general structure of amino acid.
B) With the help of neatly labelled diagrams explain the peptide bond.
4. A) What are stereoisomers?
B) Explain different types of glycosidic bonds with suitable examples?
C) Mutarotation.
5. Write a detailed note on plant and animal storage polysaccharides with suitable diagrams and examples.
6. A) What is disaccharide. Explain with two suitable examples.
B) Give a detailed account on glycoconjugates.
7. A) Describe classification of lipids?
B) Explain the importance of lipids as signalling molecules.
8. A) Enlist water and fat soluble vitamins. Write a detailed note on classification of vitamins with examples.
9. A) Describe and draw nucleosides and nucleotides.
B) Write the experimental evidences showing nucleic acids as genetic material.
10. A) Describe and draw the structure of Watson-Crick Model of DNA.
B) Explain the chemical basis behind the increased U.V. absorption of denatured DNA.
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