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IGNOU MCH-15 (January 2025 – December 2025) Assignment Questions
1. a) What is the name of the system of classification applied for the domains of life? List the common features of prokaryotes and eukaryotes.
b) Which cell organelle is called the “control centre”? Describe its composition.
2. a) Write the step wise reactions of formation of a glycoside taking glucose as an example.
b) What are hormones? Name the classes of steroid hormones along with their important functions.
3. a) Describe how the cell membrane regulates the movement of various molecules into and out of the cell.
b) Differentiate between the essential and non essential amino acids. Describe the amphoteric nature of amino acids.
4. a) Explain the geometry of the peptide backbone. Illustrate your answer.
b) Describe the tertiary structure of proteins in terms of the bonds and forces that stabilise the structure.
5. a) Why the metabolism is called the ‘intermediary metabolism’? Describe the convergent and divergent nature of metabolism.
b) Explain what is meant by high energy phosphate compounds and what their significance is in the living systems.
6. a) What is EMP pathway? Explain the isomerisation reaction of glycolysis giving the catalyst involved.
b) Explain the role of constituent enzymes of pyruvate dehydrogenase complex involved in the conversion of pyruvate into acetyl-CoA.
7. a) What are ketone bodies? Explain their significance to human beings.
b) Draw a diagrammatic sketch of the urea cycle indicating the products and enzymes involved.
8. a) Give a comparative account of purine and pyrimidine nucleotide degradation.
b) Define immunity. Differentiate between innate and acquired immunity.
9. a) What is the significance of antigen-antibody interaction? Describe in brief the mechanisms involved in antigen-antibody interaction.
b) Name the enzymes involved in DNA replication and describe their role in this process.
10. Write short notes on the following :
a) Water and electrolyte balance in living systems
b) Blood group substances
c) Nucleosides and nucleotides
d) Homeostasis
IGNOU MCH-15 (January 2024 – December 2024) Assignment Questions
1. a) What is meant by domains of life? Describe in brief the different domains of life.
b) Compare and contrast the cellular organisation in prokaryotes and eukaryotes.
2. a) Describe the method of separating the subcellular organelles. Illustrate your answer.
b) Define pH and buffer. How are the two related? Name the two important biological buffers in the human body.
3. a) Draw and explain the open chain and ring structures of monosaccharides taking a suitable example.
b) Describe the structure and classification of fatty acids giving examples.
4. a) What are zwitterions? Explain taking an amino acid as the example. How does a zwitterion relate to the isoelectric point of an amino acid?
b) Differentiate between a nucleotide and nucleoside giving their structures.
5. a) Describe the structural basis for the role of ATP as the energy carrier in biological systems. Write the reaction involved.
b) What are coupling reactions? Explain their significance in the biological systems.
6. a) Differentiate between glycolysis and gluconeogenesis writing the reactions in which these two differ from each other.
b) Describe the central role of TCA cycle in the metabolism of biomolecules in a living system.
7. a) Name the three stages of catabolism of amino acids and give a schematic representation of the same.
b) Describe the fate of uric acid during the degeneration of purine nucleotides.
8. a) What is meant by immunity? Enumerate the different levels of defense in the body.
b) Differentiate between an antigen and an antibody. Describe and illustrate the structure of an antibody.
9. a) Describe any one experiment which proved that ‘DNA is the genetic material’.
b) Explain the process of DNA replication. Illustrate your answer.
10. a) Describe the structure and role of ribosomes in protein biosynthesis.
b) Describe the oxidative degradation of acyl-CoA during the degradation of fatty acids.
