IGNOU MZO-02 (January 2025 – December 2025) Assignment Questions
1. How did Mendel’s use of controlled crossbreeding in pea plants lead to the discovery of dominant and recessive traits? Describe the Mendel’s laws of heredity.
2. What is epistasis, and how does it affect the expression of traits? Provide examples to describe the different types of epistasis, such as dominant epistasis and recessive epistasis.
3. What are the different types of mutations and how do they affect the genetic code and protein synthesis?
4. How do transcription factors and enhancers regulate gene expression in eukaryotic cells, and what role do epigenetic modifications such as DNA methylation and histone modification play in this process?
5. Compare the X-Y sex determination system with the Z-W sex determination system, providing suitable examples.
6. Describe the key cytogenetic techniques of karyotyping and fluorescence in situ hybridization (FISH) used to identify chromosomal abnormalities.
7. What are cloning vectors? How are they used in recombinant DNA technology to insert foreign genes into host cells? Discuss the different types of cloning vectors and their features.
8. Compare the processes of constructing a genomic library and a cDNA library. Which type of library is used for studying gene expression?
9. What are transgenic animals? What are the key techniques used in the creation of transgenic animals, and how do these methods contribute to advancements in fields such as medicine and agriculture?
10. What is gene therapy and how does it work to treat genetic disorders? Discuss the various types of gene therapy and their applications.
IGNOU MZO-02 (January 2024 – December 2024) Assignment Questions
1. Explain the Mendel’s classical experiments and laws of heredity.
2. Describe the different types of sex-linked inheritance patterns.
3. What is gene? Explain “One gene-one enzyme hypothesis” with the help of a suitable diagram.
4. Explain the phenomena of linkage and crossing over. Add a note on recombination frequency as a measure to distance between genes.
5. What is mutation? Describe the two general classes of gene mutations.
6. What are transcription factors? Explain the role of different “general” and “specific” transcription factors present in eukaryotes.
7. Describe sex determination and its types. Add a note on sex determination in C. elegans.
8. Write a note on diseases and syndromes due to changes in chromosome numbers.
9. What are transgenic plants? With the help of a suitable diagram describe the technique of Agrobacterium tumefacines – medicated transformation for the development of transgenic plants.
10. Describe the technique of CRISPR/Cas 9 based targeted genome editing.
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