PLEASE MATCH YOUR ASSIGNMENT QUESTIONS ACCORDING TO YOUR SESSION
IGNOU MZO-05 (January 2024 – December 2024) Assignment Questions
1. What are introns and exons? Discuss the evolution of proteins by exon shuffling with illustrations.
2. Discuss with diagrams the different types of repeat elements present in eukaryotic genomes.
3. What is genome sequencing? Give an overview of the two broad types of genome sequencing you have studied.
4. Write short notes:
a) Multiple sequence alignment
b) cDNA-AFLP
5. Outline the basic principles of Northern blotting and GeneCalling.
6. What is peptide sequencing? Discuss with schematic representation, Edman degradation method of peptide sequencing. Mention its advantages and disadvantages.
7. Elaborate the different methods used for ionization of proteins during mass spectrometry.
8. Write an account on the Human Genome Project, with special reference to the analysis, recent advances and importance in medical sciences.
9. What is meant by gene silencing? Discuss the components of gene silencing. Write an account of homology-dependent gene silencing.
10. Describe with proper diagrams, the technique of Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) and its applications.